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Dalfampridine Part D coverage 2027

Dalfampridine is a generic drug. What agents check before quoting it: how many 2027 Part D plans cover it, on which tier, with what restrictions and copays, by plan type, carrier and state.

Coverage at a glance

In 2027, 4,608 of 5,492 Medicare Part D and Medicare Advantage drug plans (83.9%) list Dalfampridine on their formulary, across 279 of 286 formularies. The most common placement is tier 3 (3,697 plans, 80.2% of those covering it). 3,438 of the covering plans require prior authorization (74.6%), 0 step therapy and 3,715 a quantity limit.

What a 30-day fill costs

1,030 covering plans charge a flat copay for a 30-day supply at a preferred retail pharmacy after the deductible — median $5, 483 of them $0; 3,578 charge coinsurance instead — median 22% of the drug's cost. Once a member's out-of-pocket drug spending reaches $2,400 in 2027, covered drugs cost $0 for the rest of the year.

What changed since 2026

2026: 4,598 of 5,496 plans covered it (83.7%); 2027: 4,608 of 5,492 (83.9%).

Of 4,367 plans offered in both years, 0 added it to the formulary and 0 dropped it.

Among plans covering it both years, 80 moved it to a higher tier and 391 to a lower one; 1 added prior authorization and 13 removed it.

Tier placement

TierPlans
Tier 1389
Tier 2498
Tier 33,697
Tier 424

By plan type

Plan typePlans coveringSharePrior auth
Stand-alone Part D (PDP)221 of 32368.4%67%
Medicare Advantage with drugs (MA-PD)2,658 of 3,20083.1%78%
Special needs plans (SNP)1,729 of 1,96987.8%70.4%

By carrier

CarrierPlans coveringUsual tierPrior auth
Humana0 of 846No tier listed0
UnitedHealthcare830 of 830Tier 30
Devoted Health728 of 728Tier 3728
Aetna Medicare631 of 631Tier 3631
Wellcare268 of 268Tier 1268
HealthSpring226 of 226Tier 3226
Kaiser Permanente112 of 112Tier 216
SCAN Health Plan83 of 83Tier 383
Highmark Blue Cross Blue Shield or Highmark Blue Shield80 of 80Tier 380
Alignment Health Plan77 of 77Tier 377
Anthem Blue Cross and Blue Shield74 of 74Tier 374
Wellpoint63 of 63Tier 363
Priority Health Medicare40 of 40Tier 340
CarePlus Health Plans, Inc.0 of 37No tier listed0
Zing Health36 of 36Tier 236
Capital Blue Cross35 of 35Tier 335
Prominence Health Plan29 of 29Tier 229
Medica27 of 27Tier 327
Anthem HealthKeepers26 of 26Tier 326
Blue Cross Blue Shield of Michigan26 of 26Tier 326

By state

StatePlans coveringShare
Alabama95 of 11483.3%
Alaska6 of 966.7%
American Samoa1 of 1100%
Arizona125 of 14785%
Arkansas64 of 8575.3%
California367 of 39792.4%
Colorado87 of 10682.1%
Connecticut47 of 5487%
Delaware36 of 4383.7%
District of Columbia11 of 1291.7%
Florida430 of 54578.9%
Georgia114 of 14976.5%
Guam1 of 1100%
Hawaii42 of 5084%
Idaho34 of 4575.6%
Illinois104 of 13278.8%
Indiana108 of 13878.3%
Iowa55 of 6485.9%
Kansas65 of 8477.4%
Kentucky79 of 12165.3%
Louisiana89 of 12571.2%
Maine37 of 5271.2%
Maryland42 of 4985.7%
Massachusetts82 of 8992.1%
Michigan165 of 18290.7%
Minnesota60 of 6395.2%
Mississippi80 of 10476.9%
Missouri136 of 17080%
Montana10 of 2737%
Nebraska43 of 5184.3%
Nevada81 of 10081%
New Hampshire16 of 2564%
New Jersey61 of 7383.6%
New Mexico54 of 6879.4%
New York205 of 21595.3%
North Carolina147 of 17683.5%
North Dakota23 of 2688.5%
Northern Mariana Islands1 of 1100%
Ohio149 of 17187.1%
Oklahoma58 of 8171.6%
Oregon79 of 9285.9%
Pennsylvania296 of 32391.6%
Puerto Rico64 of 64100%
Rhode Island26 of 2989.7%
South Carolina66 of 8974.2%
South Dakota27 of 3090%
Tennessee135 of 15686.5%
Texas338 of 40783%
U.S. Virgin Islands1 of 1100%
Utah38 of 5371.7%
Vermont7 of 1450%
Virginia100 of 14469.4%
Washington95 of 11483.3%
West Virginia52 of 6975.4%
Wisconsin77 of 9680.2%
Wyoming8 of 1361.5%

Medicare usage

Medicare Part D paid for 151,426 30-day fills of Dalfampridine in 2024 for about 17,196 enrollees, at an average total cost of $330.82 per 30-day fill (CMS Part D Prescribers by Geography and Drug, national).

Agent Tools

Price Dalfampridine and the rest of a client's list on every plan in their county.

Estimate Dalfampridine costs by plan

Free tools for licensed insurance agents. Data from CMS public files; verify with plan documents before advising a client.

Counts are over every Medicare Advantage drug plan and stand-alone Part D plan in the CMS monthly formulary files, excluding employer plans. A plan counts as covering a drug when any strength or form of it is on the plan’s formulary; the tier, prior authorization, step therapy and quantity limit shown are the most favorable version on that formulary. Copays are for a 30-day supply at a preferred retail pharmacy after the deductible. This is a reference for licensed agents, not a plan recommendation; verify with the plan’s formulary before advising a client. Source: CMS Part D formulary files (release 10/08/2026). CMS formulary data.